Origen is the first author in the to arrange a critical edition of the Old Testament. He organized in six columns the text of the Old Testament, in Hebrew and Greek, and incorporated the of Aquila (a of the time of Hadrian), and the of and the Septuagint.
According to Eusebius, he later published another edition containing only four columns that is called the Tetrapla. This scientific work was used by many Fathers, among them in his commentaries on the Psalms, as well as Eusebius of Caesarea and Jerome for his commentaries on the Psalms. It is regretful that only a fragment of this work has survived. A Syriac of the text of Paul, the Bishop of Tella, survives.